Procedures

Testosterone replacement therapy

Procedures

Testosterone replacement therapy

Appointments1 every 3-4 months

All currently available intramuscular, subcutaneous, transdermal, nasal and oral testosterone administration treatments may be used. These treatments are all covered by the RAMQ’s provincial drug insurance plan. The treatment type should be an informed and joint decision between the physician and the patient.

There is now a new treatment with subcutaneous testosterone implants.

This treatment is not covered by the Quebec drug insurance plan (RAMQ).

What is the alternative treatment of testosterone administered in the nose?

Natesto is an intranasal gel (5.5 mg testosterone) administered in each nostril twice daily at 6-hour intervals.

The testosterone used is bioidentical, which means the hormones in the drug are chemically identical to the ones in your body. This treatment is regularly used but may cause a metallic taste in the mouth and nasal problems such as abnormal or unpleasant smells, continuous runny nose, congestion, sneezing, nosebleeds, discomfort in the nose, scabs or dryness.

What is the replacement treatment for testosterone administered on the skin?

Androgel is a gel sachet administered daily in the morning on the dry skin of the shoulders, arms or abdomen.

Testim (testosterone gel 1 per cent) is a tube filled with 50 mg of testosterone gel, applied in the morning on clean, dry skin of the shoulders or arms.

Androgel and Testim should be applied daily and completely absorbed before wearing clothing. After application, it’s important to wash your hands immediately with soap and water. Testosterone in these 2 drugs is also bioidentical. The 2 treatments are frequently used, and their absorption may vary from one patient to another.

What is testosterone replacement therapy given with a patch?

Androderm (2.5 mg and 5 mg testosterone transdermal system) is a single 5 mg patch or 2, 2.5 mg patches applied every night (at approximately 10 p.m.) to clean dry skin of the back, the abdomen, arms or thighs.

It’s essential to rotate application sites regularly to avoid irritation and not apply the patch to an area previously used until at least 7 days have elapsed. It’s a treatment rarely used since the patches fall off easily when patients sweat.

What is the replacement therapy for testosterone given by injection?

Delastestryl (testosterone enanthate 200 mg/ml) is an injection of 100 to 400 mg every 1 to 4 weeks.

Depo-testosterone (testosterone cypionate 100 mg/ml for injection and generic) is usually prescribed as a 200 mg injection administered every two weeks.

These are synthetic and non-bioidentical testosterone treatments. These treatments are regularly used when the gels aren’t effective enough. They have a jagged effect, as they’re more effective during the first days and less effective in the final days before a new injection. They have a high rate of erythrocytosis (thicker blood by an excess of red blood cells) and increased platelet aggregation. These treatments can also increase the risk of coronary clots.

Is there an oral medication for testosterone replacement therapy?

Andral (testosterone undecanoate) is a 40 mg capsule to be taken daily in 2 or 3 doses with food.

This treatment is rarely used because it’s hard on the liver and difficult to absorb, as well as for its short action and low effectiveness.

What is the replacement treatment of testosterone in bioidentical GRANULES?

Les Cliniques Marois favours this treatment for its simplicity, efficiency and stability.

These are small bioidentical testosterone granules implanted in the fatty part of the buttock at 4- to 5-month intervals (depending on the activity level).

Hormone replacement therapy bioidentical in men

Would you like to make an appointment, or do you have any questions? Write to us and we will get back to you as soon as possible!

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