DIAGNOSTICS

Peyronie’s disease | Curvature of the penis

The penis has two corpus cavernosum, which are sponge-like regions of erectile tissue that surround the urethra and extend from the base of the penis to the glans. The corpus cavernosum are covered with thick, elastic tissue called tunica albuginea. During an erection, as penis volume grows as a result of increased blood flow in the tissues, the tunica albuginea becomes stretched. Peyronie’s disease is caused by the formation of scar tissue in a specific area on the tunica albuginea. This scar tissue diminishes elasticity, causing curvature of the penis when erect.

The penis is comprised of two corpus cavernosum: sponge-like regions of erectile tissue that surround the urethra and extend from the base of the penis to the glans. The corpus cavernosum are covered with thick, elastic tissue called tunica albuginea. During an erection, the tunica albuginea stretches and increases in volume. Peyronie’s disease is caused by the formation of scar tissue on the tunica albuginea, causing curvature of the penis when erect.

What causes Peyronie’s disease?
The condition has no definite known cause. However, trauma to the penis seems to play a role in 37% of cases.
What are the medical risk factors?
In 10% of cases, Peyronie’s disease is linked to Dupuytren’s disease. Additionally, diabetes, smoking, Paget’s disease, rheumatoid arthritis and the use of beta-blockers can all contribute to the development of Peyronie’s disease.
How common is Peyronie’s disease?
The prevalence of Peyronie’s disease in the general population is estimated to be about 7%. The average age of the onset of the disease is 53. The disease doesn’t typically develop in men under 40.
How does Peyronie’s disease develop?
The curved or crooked penis that’s characteristic of Peyronie’s disease can progress in a number of possible ways. In some cases, the curvature of the penis spontaneously corrects itself with time. In other cases, it develops into a major deformity. Moreover, it’s difficult to determine how the curvature will evolve in the early stages of the disease.

Typically, Peyronie’s disease develops in two stages.

In the acute or active stage, changes in the shape of the erect penis occur and the patient may experience penile pain and/or notice lumps in the penis. The pain may be spontaneous and felt either continuously or only during erections. In most cases, the pain goes away within 12 to18 months.

In the chronic or stable stage, curvature generally doesn’t change — it neither worsens nor improves. Typically, the patient no longer experiences any pain.
How is Peyronie’s disease diagnosed?
A diagnosis is typically made after a physical examination of the patient and a review of his medical history. An erection can be artificially induced by a medical professional to accurately determine the degree of curvature.
What medical treatments are available for Peyronie’s disease?
One of several treatments may be administered for Peyronie’s disease. Depending on its stage of development, a doctor may recommend:
  • Shock wave therapy. This is a non-surgical treatment that helps to reduce pain.
  • Collagenase injections. This treatment has can decrease penis curvature as well as treat erectile dysfunction. It’s fairly costly, however, and involves about four treatment sessions.
  • Platelet-rich plasma injections in conjunction with hyaluronic acid injections. This is a new treatment recently approved by Health Canada that involves drawing a blood sample from the patient, centrifuging the blood to separate the plasma and injecting the plasma into the scar tissue or plaques in the penis.
  • Penile plication. This is a surgical procedure designed to straighten a bent penis
Is there a physical treatment for curvature of the penis?
Extracorporeal shock wave lithotripsy is a physical treatment that has been shown to accelerate the resolution of pain in the initial phase of the disease. This treatment is offered at Dr. Carlos Marois’ private practice. It consists of one 30-minute appointment per week over four weeks.
What treatments for Peyronie’s disease are available at a urology clinic?
  • Shock wave therapy. This is a non-surgical treatment that helps to reduce pain.
  • Conventional treatments such as professional advice and penile traction therapy
  • Drug injection
  • Shock wave therapy
  • Penile plication procedure
  • Platelet-rich plasma injections
Contact us for more information or to schedule an adult circumcision at a private clinic in Montreal, Laval, on the South Shore or in Quebec City.

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Dr. Marois is a urologist who is not a member of the Régie d’Assurance Maladie du Québec (RAMQ). As such, the clinic can not claim the RAMQ for the payment of his services. If you consult Dr Marois, you must pay for the services rendered.

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