PCA3 : Prostate Cancer Screening

This is a molecular biology test to help you determine whether a biopsy is really needed (a urine screening test that determines high or low risk of developing prostate cancer).

The test for prostate cancer gene 3 (PCA3) is a molecular biology test. It does not replace the prostate specific antigen (PSA) evaluation. The PCA3 is an additional tool to more easily determine whether a prostate biopsy is needed to diagnose prostate cancer in men with suspected prostate cancer. PCA3, unlike PSA, is specifically related to prostate cancer, which means that it is only produced by cancerous prostate cells and it is not influenced by the size of the prostate. Therefore PCA3 is better than PSA at differentiating cancer from benign or non-cancer related prostate diseases, such as benign prostatic hyperplasia (BPH) (i.e. an enlarged prostate) or prostatitis (prostate infection). The PCA3 test provides very useful information, in addition to that obtained from the PSA, to help determine whether a prostate biopsy is really necessary.

How to interpret the results of the PCA3 test?
The PCA3 test is simple: after a digital rectal exam, cancerous cells with high levels of PCA3 are evicted from the prostate and into the urine. A urine sample is then collected. This urine sample is sent to a WARNEX private laboratory that determines the PCA3 score. A high PCA3 score indicates an increased likelihood of the presence of cancerous cells, that is to say the presence of cancerous cells in the prostate. A low PCA3 score indicates a decrease in the probability of the presence of cancerous cells. If the PCA3 score is low, the biopsy can be deferred or avoided. PCA3 thus avoids many unnecessary first biopsies along with the discomfort and potential complications (pain, bleeding and infection) that arise from them.

The PCA3 test can also be performed in men who have already had one or more negative biopsies. This allows us to predict the likelihood that a repeat biopsy would be positive, or to assess the need for a repeat biopsy.

Would you like to make an appointment, or do you have any questions? Write to us and we will get back to you as soon as possible!

Dr. Marois is a urologist who is not a member of the Régie d’Assurance Maladie du Québec (RAMQ). As such, the clinic can not claim the RAMQ for the payment of his services. If you consult Dr Marois, you must pay for the services rendered.

Cancellation of appointment:

To ensure the smooth running of the clinic and a minimum of courtesy towards other patients and our staff, we ask you to notify us 48 hours in advance for the cancellation of a consultation, 5 working days in advance for a surgery at the office and 21 working days in advance for a major surgery. If these deadlines are not respected, a cancellation fee of 50% of the service will be charged.

Change of appointment:

We understand that events occur, so we ask you to provide us with at least a 24-hour notice for any change in their appointment; we will be happy to accommodate you, the best we can. However, if you fail to inform us within this timeframe or do not show up, we will charge a $ 100 fee.

Thank you for your understanding.

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